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Query: UBE2L3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2L3 0 4.870 -0.730 0.630
UBE2L3 0 4.870 -0.730 0.630 1.031 0.887

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2L3 Ubiquitylation K20 1.131 0.956 _CGMK(gl)NFR_
UBE2L3 Ubiquitylation K146 0.357 0.853 _NAEEFTKK(gl)_
UBE2L3 Ubiquitylation K131 0.407 0.848 _ADLAEEYSK(gl)DR_
UBE2L3 Ubiquitylation K235 0.591 0.087 _TVDTK(gl)QAQDLAR_
UBE2L3 Ubiquitylation K73 0.293 0.015 _TK(gl)IYHPNIDEK_
UBE2L3 Ubiquitylation K254 -0.450 -0.156 _SYGIPFIETSAK(gl)TR_
UBE2L3 Ubiquitylation K9 1.366 _LMK(gl)ELEEIRK_
UBE2L3 Ubiquitylation K64 -1.229 _IEINFPAEYPFK(gl)PPK_
UBE2L3 Ubiquitylation K96 -0.965 _GQVCLPVISAENWK(gl)PATK_
UBE2L3 Ubiquitylation K138 0.523 _FCK(gl)NAEEFTK_
UBE2L3 Ubiquitylation K150 0.275 _YGEK(gl)RPVD_

Background Information for UBE2L3:


Pubmed-UBE2L3 »
Uniprot-UBE2L3 »
Biogrid-UBE2L3 »
ProteomicsDB-UBE2L3 »

Tumorportal-UBE2L3 »
COSMIC-UBE2L3 »
GenomeRNAi-UBE2L3 »
Genecards-UBE2L3


Protein-protein Interactions for UBE2L3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARIH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBE2L3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members RWD-domain IPR006575 0
Category members UEV_N IPR008883 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2L3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2823 BRCA1-BARD1-UbcH7c complex Database 0.57


Categories featuring UBE2L3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_870 PID_BARD1_PATHWAY 0 2.44
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0070979 protein K11-linked ubiquitination Database 0.25
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0071383 cellular response to steroid hormone stimulus Database 0.08
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members Pathway Pathway_1259 BIOCARTA_PARKIN_PATHWAY 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0071385 cellular response to glucocorticoid stimulus Database 0


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