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Query: TRAF7

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRAF7 0 -1.172 -1.410 2.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRAF7 Phosphorylation S108 -0.756 -0.573 _STFS(ph)LPEEEEEPEPLVFAEQPSVK_
TRAF7 Ubiquitylation K199 -1.430 -1.568 _VAGSGK(gl)PPIFEVDPR_
TRAF7 Ubiquitylation K160 -0.315 _SEK(gl)CPVDNVK_

Background Information for TRAF7:


Pubmed-TRAF7 »
Uniprot-TRAF7 »
Biogrid-TRAF7 »
ProteomicsDB-TRAF7 »

Tumorportal-TRAF7 »
COSMIC-TRAF7 »
GenomeRNAi-TRAF7 »
Genecards-TRAF7


Protein-protein Interactions for TRAF7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAP3K2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C13orf15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC67 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD2BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGNL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COL4A3BP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CORO1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM175B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FRMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIME1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP2K5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMP10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NELL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OIP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYBU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TINAG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF764 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRAF7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members Znf_TRAF IPR001293 0
Category members Znf_RING IPR001841 0
Category members TRAF-like IPR008974 0


Protein complexes (CORUM database) featuring TRAF7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5199 Kinase maturation complex 1 Database 3.38


Categories featuring TRAF7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0043410 positive regulation of MAPK cascade Database 0.06
Category members GO Category GO:0000185 activation of MAPKKK activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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