Results for the Category
activation of MAPKKK activity
(GO:0000185)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| TAB1 | 1 | 1.890 | -0.670 | |||||
| TAB1 | 1 | 1.890 | -0.670 | 1.657 | ||||
| GADD45A | 0 | 1.050 | -0.170 | |||||
| TRAF7 | 0 | -1.410 | 2.040 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| GADD45A | Ubiquitylation | K12 | -0.515 | 0.281 | _TLEEFSAGEQK(gl)TER_ |
| GADD45A | Ubiquitylation | K29 | 0.092 | _VGDALEEVLSK(gl)ALSQR_ | |
| TAB1 | Phosphorylation | S7 | -0.170 | 0.140 | _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_ |
| TAB1 | Phosphorylation | S16 | -0.138 | 0.069 | _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_ |
| TAB1 | Ubiquitylation | K186 | -1.015 | _SYSADGK(gl)GTESHPPEDSWLK_ | |
| TAB1 | Ubiquitylation | K371 | 0.032 | _LSQLGLDAGK(gl)IK_ | |
| TAB1 | Ubiquitylation | K373 | -0.007 | _LSQLGLDAGKIK(gl)_ | |
| TRAF7 | Phosphorylation | S108 | -0.756 | -0.573 | _STFS(ph)LPEEEEEPEPLVFAEQPSVK_ |
| TRAF7 | Ubiquitylation | K160 | -0.315 | _SEK(gl)CPVDNVK_ | |
| TRAF7 | Ubiquitylation | K199 | -1.430 | -1.568 | _VAGSGK(gl)PPIFEVDPR_ |
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