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Query: TMEM67

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM67 0 1.985 -0.480 0.280

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM67 Ubiquitylation K650 1.063 0.642 _VLK(gl)AVEGEGGVR_
TMEM67 Ubiquitylation K986 0.268 _NLASK(gl)TLVDQR_

Background Information for TMEM67:


Pubmed-TMEM67 »
Uniprot-TMEM67 »
Biogrid-TMEM67 »
ProteomicsDB-TMEM67 »

Tumorportal-TMEM67 »
COSMIC-TMEM67 »
GenomeRNAi-TMEM67 »
Genecards-TMEM67


Protein-protein Interactions for TMEM67
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP1B4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD300E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFB121 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MUC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC22A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMEM67
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Growth_fac_rcpt_N_dom IPR009030 0


Protein complexes (CORUM database) featuring TMEM67
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM67
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members Disease phenotype JOUBERT_SYNDROME JOUBERT SYNDROME Database 0.07
Category members Disease phenotype BARDET-BIEDL_SYNDROME BARDET-BIEDL SYNDROME Database 0
Category members Disease phenotype COACH_syndrome COACH syndrome Database 0
Category members Disease phenotype Joubert_syndrome_with_hepatic_defect Joubert syndrome with hepatic defect Database 0
Category members Disease phenotype Meckel_syndrome Meckel syndrome Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0010826 negative regulation of centrosome duplication Database 0
Category members GO Category GO:0031005 filamin binding Database 0
Category members GO Category GO:0036038 TCTN-B9D complex Database 0
Category members GO Category GO:0042384 cilium assembly Database 0
Category members GO Category GO:0060170 ciliary membrane Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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