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Query: TLK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TLK1 0 0.299 1.190 -1.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TLK1 Phosphorylation S741 0.299 _RS(ph)NSSGNLHMAGLTASPTPPSSSIITY_

Background Information for TLK1:


Pubmed-TLK1 »
Uniprot-TLK1 »
Biogrid-TLK1 »
ProteomicsDB-TLK1 »

Tumorportal-TLK1 »
COSMIC-TLK1 »
GenomeRNAi-TLK1 »
Genecards-TLK1


Protein-protein Interactions for TLK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ASF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BATF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TLK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring TLK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TLK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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