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Query: TICAM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TICAM2 0 2.090 0.641 1.449

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for TICAM2:


Pubmed-TICAM2 »
Uniprot-TICAM2 »
Biogrid-TICAM2 »
ProteomicsDB-TICAM2 »

Tumorportal-TICAM2 »
COSMIC-TICAM2 »
GenomeRNAi-TICAM2 »
Genecards-TICAM2


Protein-protein Interactions for TICAM2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in TICAM2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TIR_dom IPR000157 0


Protein complexes (CORUM database) featuring TICAM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1714 TICAM1-TICAM2-TLR4 complex Database 0


Categories featuring TICAM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0035666 TRIF-dependent toll-like receptor signaling pathway Database 0.29
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0034138 toll-like receptor 3 signaling pathway Database 0.28
Category members GO Category GO:0034142 toll-like receptor 4 signaling pathway Database 0.27
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0002756 MyD88-independent toll-like receptor signaling pathway Database 0.25
Category members Pathway Pathway_826 REACTOME_ACTIVATED_TLR4_SIGNALLING 0 0.21
Category members Pathway Pathway_527 REACTOME_TOLL_RECEPTOR_CASCADES 0 0.17
Category members GO Category GO:0002224 toll-like receptor signaling pathway Database 0.12
Category members GO Category GO:0005770 late endosome Database 0.09
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_834 REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 0 0.04
Category members Pathway Pathway_793 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX 0 0.03
Category members Pathway Pathway_1025 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 0 0
Category members Pathway Pathway_612 KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_631 PID_IL1_PATHWAY 0 0
Category members Pathway Pathway_825 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON 0 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007249 I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0034144 negative regulation of toll-like receptor 4 signaling pathway Database 0
Category members GO Category GO:0034145 positive regulation of toll-like receptor 4 signaling pathway Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0


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