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Query: TBCD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TBCD 0 1.988 0.820 -0.650 1.428

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TBCD Ubiquitylation K913 0.550 _IMCCVAQQASEK(gl)IDR_
TBCD Ubiquitylation K299 -0.144 _LGVK(gl)LVQR_
TBCD Ubiquitylation K1076 -0.225 _LLALCK(gl)K_
TBCD Ubiquitylation K1077 -0.225 _LLALCK(gl)K_
TBCD Ubiquitylation K453 0.010 -0.719 _ALTYDEK(gl)R_
TBCD Ubiquitylation K820 -0.089 -0.799 _DGLK(gl)AIAR_
TBCD Ubiquitylation K310 -0.882 _LGLTFLK(gl)PK_
TBCD Ubiquitylation K691 -1.291 _LSLSK(gl)MPFR_
TBCD Ubiquitylation K221 -0.672 -1.403 _FITRPDVK(gl)QSK_

Background Information for TBCD:


Pubmed-TBCD »
Uniprot-TBCD »
Biogrid-TBCD »
ProteomicsDB-TBCD »

Tumorportal-TBCD »
COSMIC-TBCD »
GenomeRNAi-TBCD »
Genecards-TBCD


Protein-protein Interactions for TBCD
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKFZp686O24166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TBCD
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring TBCD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TBCD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006457 protein folding Database 4.93
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members GO Category GO:0010812 negative regulation of cell-substrate adhesion Database 0.47
Category members GO Category GO:0016328 lateral plasma membrane Database 0.41
Category members GO Category GO:0070830 tight junction assembly Database 0.36
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0043547 positive regulation of GTPase activity Database 0.21
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0048487 beta-tubulin binding Database 0.1
Category members GO Category GO:0031115 negative regulation of microtubule polymerization Database 0.08
Category members Pathway Pathway_1295 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY 0 0.07
Category members GO Category GO:0007023 post-chaperonin tubulin folding pathway Database 0
Category members GO Category GO:0034333 adherens junction assembly Database 0


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