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Query: TAF5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TAF5 0 0.644 1.390 -1.390 -2.311 0.004 0.398 1.017 0.674

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TAF5 Ubiquitylation K318 0.476 0.385 _DSYQLLK(gl)R_

Background Information for TAF5:


Pubmed-TAF5 »
Uniprot-TAF5 »
Biogrid-TAF5 »
ProteomicsDB-TAF5 »

Tumorportal-TAF5 »
COSMIC-TAF5 »
GenomeRNAi-TAF5 »
Genecards-TAF5


Protein-protein Interactions for TAF5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GSK3B Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21B Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFAP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAST3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MCAT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TAF5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members LisH_dimerisation IPR006594 0.06
Category members TFIID-su_WD40-assoc_reg IPR007582 0


Protein complexes (CORUM database) featuring TAF5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 445 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 455 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 456 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 459 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 462 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 513 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 1321 Transcription initiation factor complex (TAF5, TAF6, TAF9, TAF11, TBP) Database 0.05
Category members Corum 493 DAB complex Database 0.04
Category members Corum 470 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.02
Category members Corum 1318 Transcription initiation factor complex (TAF1, TAF5, TAF11, TAF12, TBP) Database 0
Category members Corum 155 TFIID complex Database 0
Category members Corum 3009 TFIID complex Database 0
Category members Corum 3010 TFIID subcomplex Database 0
Category members Corum 463 TFIID-beta complex Database 0
Category members Corum 469 TFIID-beta complex Database 0
Category members Corum 484 TFIID complex Database 0
Category members Corum 485 TFIID complex, B-cell specific Database 0
Category members Corum 492 DA complex Database 0
Category members Corum 508 TFIID complex Database 0
Category members Corum 509 TFIID complex Database 0
Category members Corum 514 TFIID-beta complex Database 0


Categories featuring TAF5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_370 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING 0 0.34
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0033276 transcription factor TFTC complex Database 0.06
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_856 KEGG_BASAL_TRANSCRIPTION_FACTORS 0 0
Category members GO Category GO:0005669 transcription factor TFIID complex Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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