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Query: STK24

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STK24 0 1.437 0.490 -0.300
STK24 0 1.437 0.490 -0.300 -0.371 0.364
STK24 0 1.437 0.490 -0.300 -0.052

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STK24 Phosphorylation S4 0.816 0.517 _(ac)AHS(ph)PVQSGLPGMQNLK_
STK24 Phosphorylation S4 0.269 0.161 _(ac)AHS(ph)PVAVQVPGMQNNIADPEELFTK_
STK24 Ubiquitylation K162 -0.327 0.155 _GLDYLHSEKK(gl)_
STK24 Ubiquitylation K302 -0.101 0.068 _K(gl)TSYLTELIDR_
STK24 Ubiquitylation K197 -0.399 0.038 _LADFGVAGQLTDTQIK(gl)R_
STK24 Ubiquitylation K423 -0.470 -0.024 _SIAVAEAACPGITDKMVK(gl)_
STK24 Ubiquitylation K298 0.008 -0.419 _FIVK(gl)NSK_
STK24 Ubiquitylation K255 -0.986 _VLFLIPK(gl)NNPPTLVGDFTK_
STK24 Ubiquitylation K420 -0.470 _SIAVAEAACPGITDK(gl)MVK_

Background Information for STK24:


Pubmed-STK24 »
Uniprot-STK24 »
Biogrid-STK24 »
ProteomicsDB-STK24 »

Tumorportal-STK24 »
COSMIC-STK24 »
GenomeRNAi-STK24 »
Genecards-STK24


Protein-protein Interactions for STK24
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM40A Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRPPRC Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SIKE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait WRAP53 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6V1C2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGIX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDCD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STK24
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring STK24
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring STK24
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_877 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 0 1.25
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004702 receptor signaling protein serine/threonine kinase activity Database 0.1
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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