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Query: STEAP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STEAP3 0 0.098 1.380 -1.140 -0.558 -0.578

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STEAP3 Phosphorylation S17 1.039 _PEEMDKPLISLHLVDS(ph)DSSLAK_
STEAP3 Ubiquitylation K484 -0.079 0.275 _FTLPTDHALAEK(gl)TSHV_
STEAP3 Ubiquitylation K175 -0.783 -0.882 _QVPICGDQPEAK(gl)R_
STEAP3 Ubiquitylation K472 -0.323 _ESTIK(gl)FTLPTDHALAEK_

Background Information for STEAP3:


Pubmed-STEAP3 »
Uniprot-STEAP3 »
Biogrid-STEAP3 »
ProteomicsDB-STEAP3 »

Tumorportal-STEAP3 »
COSMIC-STEAP3 »
GenomeRNAi-STEAP3 »
Genecards-STEAP3


Protein-protein Interactions for STEAP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C13orf16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM177A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBLAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RANBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIGD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEFF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STEAP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Fe3_Rdtase_TM_dom IPR013130 0
Category members ProC_N IPR028939 0


Protein complexes (CORUM database) featuring STEAP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring STEAP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0005768 endosome Database 0.29
Category members Pathway Pathway_382 KEGG_P53_SIGNALING_PATHWAY 0 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0009306 protein secretion Database 0.02
Category members Pathway Pathway_192 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING 0 0
Category members Pathway Pathway_193 REACTOME_IRON_UPTAKE_AND_TRANSPORT 0 0
Category members GO Category GO:0000293 ferric-chelate reductase activity Database 0
Category members GO Category GO:0005771 multivesicular body Database 0
Category members GO Category GO:0006826 iron ion transport Database 0
Category members GO Category GO:0006879 cellular iron ion homeostasis Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0033572 transferrin transport Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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