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Query: SLC25A5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC25A5 0 1.452 1.020 -0.380 0.159 1.543 -0.331

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC25A5 Ubiquitylation K130 -0.918 1.293 _QIFLGGVDK(gl)R_
SLC25A5 Ubiquitylation K188 0.764 _GLGDCLVK(gl)IYK_
SLC25A5 Ubiquitylation K74 0.478 _QITADK(gl)QYK_
SLC25A5 Ubiquitylation K293 -1.774 0.323 _DEGGK(gl)AFFK_
SLC25A5 Ubiquitylation K191 0.215 _IYK(gl)SDGIK_
SLC25A5 Ubiquitylation K77 0.200 _QYK(gl)GIIDCVVR_
SLC25A5 Ubiquitylation K172 -1.978 -0.228 _LAADVGK(gl)AGAER_
SLC25A5 Ubiquitylation K88 -2.095 _IPK(gl)EQGVLSFWR_
SLC25A5 Ubiquitylation K270 -2.134 _K(gl)GTDIMYTGTLDCWR_

Background Information for SLC25A5:


Pubmed-SLC25A5 »
Uniprot-SLC25A5 »
Biogrid-SLC25A5 »
ProteomicsDB-SLC25A5 »

Tumorportal-SLC25A5 »
COSMIC-SLC25A5 »
GenomeRNAi-SLC25A5 »
Genecards-SLC25A5


Protein-protein Interactions for SLC25A5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCND1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCSTN Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNJL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC25A5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aden_trnslctor IPR002113 0.38
Category members Mit_carrier IPR002067 0
Category members Mitochondrial_sb/sol_carrier IPR018108 0
Category members Mt_carrier_dom IPR023395 0


Protein complexes (CORUM database) featuring SLC25A5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF


Categories featuring SLC25A5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0050796 regulation of insulin secretion Database 0.06
Category members GO Category GO:0015853 adenine transport Database 0.03
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0015207 adenine transmembrane transporter activity Database 0


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