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Query: SH3BP5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SH3BP5 0 -1.380 0.360 -0.060

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SH3BP5 Ubiquitylation K240 -0.180 _LTLAK(gl)GEYK_
SH3BP5 Ubiquitylation K173 -0.619 _VMEAEQTK(gl)TR_
SH3BP5 Ubiquitylation K6 -0.925 _(ac)MDAALK(gl)R_
SH3BP5 Ubiquitylation K90 -1.258 _LDELVKK(gl)_
SH3BP5 Ubiquitylation K181 -1.200 _SELVHK(gl)ETAAR_

Background Information for SH3BP5:


Pubmed-SH3BP5 »
Uniprot-SH3BP5 »
Biogrid-SH3BP5 »
ProteomicsDB-SH3BP5 »

Tumorportal-SH3BP5 »
COSMIC-SH3BP5 »
GenomeRNAi-SH3BP5 »
Genecards-SH3BP5


Protein-protein Interactions for SH3BP5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SH3BP5
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SH3BP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SH3BP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0004860 protein kinase inhibitor activity Database 0.03
Category members Pathway Pathway_540 PID_BCR_5PATHWAY 0 0
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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