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Query: SETD3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SETD3 1 5.487 -0.570 0.790 4.968 0.048

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SETD3 Ubiquitylation K439 -0.319 _ASLLLK(gl)TYK_

Background Information for SETD3:


Pubmed-SETD3 »
Uniprot-SETD3 »
Biogrid-SETD3 »
ProteomicsDB-SETD3 »

Tumorportal-SETD3 »
COSMIC-SETD3 »
GenomeRNAi-SETD3 »
Genecards-SETD3


Protein-protein Interactions for SETD3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SETD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BPHL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SETD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX13A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SETD3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SET_dom IPR001214 0.29
Category members Rubisco_LSMT_subst-bd IPR015353 0.04


Protein complexes (CORUM database) featuring SETD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SETD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042800 histone methyltransferase activity (H3-K4 specific) Database 0.73
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0001102 RNA polymerase II activating transcription factor binding Database 0.31
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0018027 peptidyl-lysine dimethylation Database 0.22
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0018023 peptidyl-lysine trimethylation Database 0.11
Category members GO Category GO:0018026 peptidyl-lysine monomethylation Database 0.05
Category members GO Category GO:0051149 positive regulation of muscle cell differentiation Database 0.04
Category members GO Category GO:0010452 histone H3-K36 methylation Database 0.03
Category members GO Category GO:0046975 histone methyltransferase activity (H3-K36 specific) Database 0


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