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Query: SCYL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCYL2 0 -2.381 0.190 0.660 -1.737 -0.391 -0.661 -1.365 -0.253

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SCYL2 Phosphorylation S677 0.455 0.911 _RAS(ph)LTLEEK_

Background Information for SCYL2:


Pubmed-SCYL2 »
Uniprot-SCYL2 »
Biogrid-SCYL2 »
ProteomicsDB-SCYL2 »

Tumorportal-SCYL2 »
COSMIC-SCYL2 »
GenomeRNAi-SCYL2 »
Genecards-SCYL2


Protein-protein Interactions for SCYL2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPATA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SCYL2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0


Protein complexes (CORUM database) featuring SCYL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF


Categories featuring SCYL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0008333 endosome to lysosome transport Database 0.49
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0002092 positive regulation of receptor internalization Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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