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Query: RUSC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RUSC1 0 -0.990 0.280 -0.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RUSC1 Ubiquitylation K511 -0.990 _NLVQK(gl)AQLGDSR_
RUSC1 Ubiquitylation K803 -1.519 _LFGVPGGPAENENGALK(gl)SR_

Background Information for RUSC1:


Pubmed-RUSC1 »
Uniprot-RUSC1 »
Biogrid-RUSC1 »
ProteomicsDB-RUSC1 »

Tumorportal-RUSC1 »
COSMIC-RUSC1 »
GenomeRNAi-RUSC1 »
Genecards-RUSC1


Protein-protein Interactions for RUSC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM83H Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PIP4K2C Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2S Cat. description Hein, Mann, Cell 2015


Protein Domains in RUSC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members Run IPR004012 0


Protein complexes (CORUM database) featuring RUSC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RUSC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members Pathway Pathway_1006 PID_MAPK_TRK_PATHWAY 0 0
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0


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