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Query: RAB1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB1A 0 2.626 0.980 -0.460 -0.532
RAB1A 0 2.626 0.980 -0.460 1.641 -1.484 0.560 0.491

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB1A Ubiquitylation K131 0.790 _LLVGNKCDLTTK(gl)K_
RAB1A Phosphorylation S2 -0.429 0.634 _(ac)S(ph)SM(ox)NPEYDYLFK_
RAB1A Phosphorylation S3 -0.429 0.634 _(ac)S(ph)SM(ox)NPEYDYLFK_
RAB1A Ubiquitylation K119 0.581 0.444 _YASENVNK(gl)LLVGNK_
RAB1A Ubiquitylation K213 -0.059 0.420 _DILLK(gl)SGGR_
RAB1A Ubiquitylation K163 0.199 _LLLGNK(gl)CDMEAK_
RAB1A Ubiquitylation K187 0.229 0.152 _MGPGATAGGAEK(gl)SNVK_
RAB1A Ubiquitylation K191 -0.108 0.036 _SNVK(gl)IQSTPVK_
RAB1A Ubiquitylation K58 -0.012 -0.593 _TIELDGK(gl)TIK_
RAB1A Ubiquitylation K61 -0.593 _TIELDGK(gl)TIK_
RAB1A Ubiquitylation K132 -0.154 _LLVGNKCDLTTKK(gl)_
RAB1A Ubiquitylation K174 -0.188 _VQK(gl)EQADKLAR_

Background Information for RAB1A:


Pubmed-RAB1A »
Uniprot-RAB1A »
Biogrid-RAB1A »
ProteomicsDB-RAB1A »

Tumorportal-RAB1A »
COSMIC-RAB1A »
GenomeRNAi-RAB1A »
Genecards-RAB1A


Protein-protein Interactions for RAB1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait GDI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members SRP_receptor_beta_su IPR019009 0.13
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring RAB1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAB1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0047496 vesicle transport along microtubule Database 0.19
Category members Pathway Pathway_1273 BIOCARTA_RAB_PATHWAY 0 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0042742 defense response to bacterium Database 0.06
Category members GO Category GO:0000045 autophagic vacuole assembly Database 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030252 growth hormone secretion Database 0


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