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Query: RAB10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB10 0 1.219 -0.280 -0.200 1.641 -1.484 0.560 0.491
RAB10 0 1.219 -0.280 -0.200 -0.051 0.529 0.549

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB10 Ubiquitylation K213 -0.059 0.420 _DILLK(gl)SGGR_
RAB10 Ubiquitylation K163 0.199 _LLLGNK(gl)CDMEAK_
RAB10 Ubiquitylation K102 -0.105 _SFENISK(gl)WLR_
RAB10 Ubiquitylation K174 -0.188 _VQK(gl)EQADKLAR_

Background Information for RAB10:


Pubmed-RAB10 »
Uniprot-RAB10 »
Biogrid-RAB10 »
ProteomicsDB-RAB10 »

Tumorportal-RAB10 »
COSMIC-RAB10 »
GenomeRNAi-RAB10 »
Genecards-RAB10


Protein-protein Interactions for RAB10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GDI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GDI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring RAB10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAB10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0030670 phagocytic vesicle membrane Database 0.37
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0043001 Golgi to plasma membrane protein transport Database 0.32
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0000145 exocyst Database 0
Category members GO Category GO:0006893 Golgi to plasma membrane transport Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0031489 myosin V binding Database 0
Category members GO Category GO:0032593 insulin-responsive compartment Database 0
Category members GO Category GO:0045200 establishment of neuroblast polarity Database 0
Category members GO Category GO:0055038 recycling endosome membrane Database 0


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