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Query: PURB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PURB 1 5.045 -1.320 2.550

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PURB Phosphorylation S6 -0.526 0.688 _(ac)ADGDS(ph)GSERGGGGGPCGFQPASR_
PURB Phosphorylation S304 0.666 0.610 _RGGGSGGGEES(ph)EGEEVDED_
PURB Phosphorylation S8 0.527 _(ac)ADGDSGS(ph)ERGGGGGPCGFQPASR_
PURB Phosphorylation S100 0.095 0.006 _DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPR_
PURB Phosphorylation S101 -0.621 -0.506 _DSLGDFIEHYAQLGPSS(ph)PEQLAAGAEEGGGPR_
PURB Ubiquitylation K70 1.141 _IAEVGAGGSK(gl)SR_

Background Information for PURB:


Pubmed-PURB »
Uniprot-PURB »
Biogrid-PURB »
ProteomicsDB-PURB »

Tumorportal-PURB »
COSMIC-PURB »
GenomeRNAi-PURB »
Genecards-PURB


Protein-protein Interactions for PURB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CNOT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPSA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PURB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PUR_DNA_RNA-bd IPR006628 0


Protein complexes (CORUM database) featuring PURB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PURB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0005662 DNA replication factor A complex Database 0.35
Category members GO Category GO:0045637 regulation of myeloid cell differentiation Database 0.32
Category members GO Category GO:0046332 SMAD binding Database 0


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