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Query: PURA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PURA 0 1.815 -0.470 0.870 0.337 -0.566 0.873

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PURA Ubiquitylation K97 0.301 _IAEVGAGGNK(gl)SR_

Background Information for PURA:


Pubmed-PURA »
Uniprot-PURA »
Biogrid-PURA »
ProteomicsDB-PURA »

Tumorportal-PURA »
COSMIC-PURA »
GenomeRNAi-PURA »
Genecards-PURA


Protein-protein Interactions for PURA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PURA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PUR_DNA_RNA-bd IPR006628 0


Protein complexes (CORUM database) featuring PURA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PURA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0003691 double-stranded telomeric DNA binding Database 0.62
Category members GO Category GO:0000784 nuclear chromosome, telomeric region Database 0.61
Category members GO Category GO:0006270 DNA replication initiation Database 0.57
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0005662 DNA replication factor A complex Database 0.35
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0006268 DNA unwinding involved in DNA replication Database 0.19
Category members GO Category GO:0000900 translation repressor activity, nucleic acid binding Database 0
Category members GO Category GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0032422 purine-rich negative regulatory element binding Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0046332 SMAD binding Database 0


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