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Query: PUM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PUM1 0 1.885 -1.440 1.740 -0.867 -1.033 -0.052

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PUM1 Ubiquitylation K754 -0.441 0.520 _DSLTGSSDLYK(gl)R_
PUM1 Phosphorylation S745 0.731 0.490 _RDS(ph)LTGSSDLYK_
PUM1 Phosphorylation S842 -0.409 -0.158 _SASSASSLFS(ph)PSSTLFSSSR_
PUM1 Ubiquitylation K830 -0.770 -0.249 _YISAAPGAEAK(gl)YR_
PUM1 Ubiquitylation K187 0.356 -0.507 _AMGEQLLPGKK(gl)_
PUM1 Phosphorylation S839 -0.915 _SASSASS(ph)LFSPSSTLFSSSR_
PUM1 Phosphorylation T747 0.718 _RDSLT(ph)GSSDLYK_
PUM1 Ubiquitylation K1001 -0.445 _ELDGHVLK(gl)CVK_

Background Information for PUM1:


Pubmed-PUM1 »
Uniprot-PUM1 »
Biogrid-PUM1 »
ProteomicsDB-PUM1 »

Tumorportal-PUM1 »
COSMIC-PUM1 »
GenomeRNAi-PUM1 »
Genecards-PUM1


Protein-protein Interactions for PUM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait CELF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLASRP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PUM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Pumilio_RNA-bd_rpt IPR001313 0


Protein complexes (CORUM database) featuring PUM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PUM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0006892 post-Golgi vesicle-mediated transport Database 0.74
Category members GO Category GO:0006417 regulation of translation Database 0


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