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Query: PRDX5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRDX5 0 0.307 0.930 -0.480 -1.143 1.450

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PRDX5:


Pubmed-PRDX5 »
Uniprot-PRDX5 »
Biogrid-PRDX5 »
ProteomicsDB-PRDX5 »

Tumorportal-PRDX5 »
COSMIC-PRDX5 »
GenomeRNAi-PRDX5 »
Genecards-PRDX5


Protein-protein Interactions for PRDX5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC15 Cat. description Hein, Mann, Cell 2015
Category members IP bait BOD1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CETN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FERMT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C4 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAGEA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH7 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA10 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDC80 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDHB15 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SESTD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM32 Cat. description Hein, Mann, Cell 2015


Protein Domains in PRDX5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Redoxin IPR013740 0.19
Category members Thioredoxin-like_fold IPR012336 0.16
Category members AhpC/TSA IPR000866 0.13


Protein complexes (CORUM database) featuring PRDX5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRDX5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051920 peroxiredoxin activity Database 0.94
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members GO Category GO:0016209 antioxidant activity Database 0.06
Category members GO Category GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Database 0.05
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members GO Category GO:0004601 peroxidase activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0016480 negative regulation of transcription from RNA polymerase III promoter Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0032967 positive regulation of collagen biosynthetic process Database 0
Category members GO Category GO:0034614 cellular response to reactive oxygen species Database 0
Category members GO Category GO:0042744 hydrogen peroxide catabolic process Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0
Category members GO Category GO:0051354 negative regulation of oxidoreductase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0070995 NADPH oxidation Database 0


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