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Query: PPP2R2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP2R2B 0 1.472 -0.630 1.060 -0.611 -0.009 -0.066 -0.157 -0.064

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP2R2B Ubiquitylation K62 1.437 -0.118 _VVIFQQEQENK(gl)IQSHSR_

Background Information for PPP2R2B:


Pubmed-PPP2R2B »
Uniprot-PPP2R2B »
Biogrid-PPP2R2B »
ProteomicsDB-PPP2R2B »

Tumorportal-PPP2R2B »
COSMIC-PPP2R2B »
GenomeRNAi-PPP2R2B »
Genecards-PPP2R2B


Protein-protein Interactions for PPP2R2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP2R2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members PP2A_PR55 IPR000009 0


Protein complexes (CORUM database) featuring PPP2R2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPP2R2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_865 PID_ATR_PATHWAY 0 3.46
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members GO Category GO:0000159 protein phosphatase type 2A complex Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0008601 protein phosphatase type 2A regulator activity Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0033554 cellular response to stress Database 0
Category members GO Category GO:0034047 regulation of protein phosphatase type 2A activity Database 0
Category members GO Category GO:0043525 positive regulation of neuron apoptotic process Database 0
Category members GO Category GO:0043653 mitochondrial fragmentation involved in apoptotic process Database 0


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