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Query: PPIB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPIB 1 2.378 -0.320 1.070 1.818 -1.512 0.460 0.205

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPIB Ubiquitylation K165 0.337 _TAWLDGK(gl)HVVFGK_
PPIB Ubiquitylation K195 -0.826 _DKPLK(gl)DVIIADCGK_

Background Information for PPIB:


Pubmed-PPIB »
Uniprot-PPIB »
Biogrid-PPIB »
ProteomicsDB-PPIB »

Tumorportal-PPIB »
COSMIC-PPIB »
GenomeRNAi-PPIB »
Genecards-PPIB


Protein-protein Interactions for PPIB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015


Protein Domains in PPIB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyclophilin-type_PPIase_dom IPR002130 0.54
Category members Cyclophilin-like_dom IPR029000 0.54


Protein complexes (CORUM database) featuring PPIB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPIB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Disease phenotype Osteogenesis_imperfecta_type_4 Osteogenesis imperfecta type 4 Database 0.29
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0000413 protein peptidyl-prolyl isomerization Database 0.25
Category members Disease phenotype Osteogenesis_imperfecta_type_2 Osteogenesis imperfecta type 2 Database 0.23
Category members Disease phenotype Osteogenesis_imperfecta_type_3 Osteogenesis imperfecta type 3 Database 0.13
Category members Pathway Pathway_415 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION 0 0.09
Category members Pathway Pathway_414 REACTOME_COLLAGEN_FORMATION 0 0
Category members Pathway Pathway_476 PID_SYNDECAN_1_PATHWAY 0 0
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0042277 peptide binding Database 0


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