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Query: PPARGC1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPARGC1B 0 0.617 0.740 -0.460

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPARGC1B Phosphorylation S524 0.617 _ELGS(ph)PTDEDSGQDQQLLR_

Background Information for PPARGC1B:


Pubmed-PPARGC1B »
Uniprot-PPARGC1B »
Biogrid-PPARGC1B »
ProteomicsDB-PPARGC1B »

Tumorportal-PPARGC1B »
COSMIC-PPARGC1B »
GenomeRNAi-PPARGC1B »
Genecards-PPARGC1B


Protein-protein Interactions for PPARGC1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DNAJC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPARGC1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34


Protein complexes (CORUM database) featuring PPARGC1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPARGC1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0010694 positive regulation of alkaline phosphatase activity Database 0.65
Category members GO Category GO:0016592 mediator complex Database 0.53
Category members GO Category GO:0042327 positive regulation of phosphorylation Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0045672 positive regulation of osteoclast differentiation Database 0.11
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members GO Category GO:0007015 actin filament organization Database 0.08
Category members GO Category GO:0006390 transcription from mitochondrial promoter Database 0.07
Category members GO Category GO:0030520 intracellular estrogen receptor signaling pathway Database 0.06
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members GO Category GO:0030546 receptor activator activity Database 0.04
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0001503 ossification Database 0
Category members GO Category GO:0030331 estrogen receptor binding Database 0
Category members GO Category GO:0034614 cellular response to reactive oxygen species Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0045780 positive regulation of bone resorption Database 0
Category members GO Category GO:0050682 AF-2 domain binding Database 0
Category members GO Category GO:0051591 response to cAMP Database 0
Category members GO Category GO:0060346 bone trabecula formation Database 0


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