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Query: PNPLA8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PNPLA8 0 0.589 0.270 -0.360 -0.075 0.032 -0.336 0.525 0.443

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PNPLA8:


Pubmed-PNPLA8 »
Uniprot-PNPLA8 »
Biogrid-PNPLA8 »
ProteomicsDB-PNPLA8 »

Tumorportal-PNPLA8 »
COSMIC-PNPLA8 »
GenomeRNAi-PNPLA8 »
Genecards-PNPLA8


Protein-protein Interactions for PNPLA8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait KAT6A Cat. description Hein, Mann, Cell 2015
Category members IP bait PCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PLK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3B Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015


Protein Domains in PNPLA8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Patatin/PLipase_A2-rel IPR002641 0
Category members Acyl_Trfase/lysoPLipase IPR016035 0


Protein complexes (CORUM database) featuring PNPLA8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PNPLA8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0001516 prostaglandin biosynthetic process Database 0.09
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0034638 phosphatidylcholine catabolic process Database 0.04
Category members Pathway Pathway_495 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC 0 0.03
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_161 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_494 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004622 lysophospholipase activity Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006631 fatty acid metabolic process Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0019369 arachidonic acid metabolic process Database 0
Category members GO Category GO:0036151 phosphatidylcholine acyl-chain remodeling Database 0
Category members GO Category GO:0036152 phosphatidylethanolamine acyl-chain remodeling Database 0
Category members GO Category GO:0043651 linoleic acid metabolic process Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0
Category members GO Category GO:0047499 calcium-independent phospholipase A2 activity Database 0
Category members GO Category GO:0050482 arachidonic acid secretion Database 0


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