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Query: PKP4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PKP4 1 2.601 -0.200 1.770
PKP4 1 2.601 -0.200 1.770 1.061 0.147

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PKP4 Phosphorylation S776 1.519 _LLGLNELDDLLGKES(ph)PSKDSEPSCWGK_
PKP4 Phosphorylation S406 0.873 0.653 _SAVS(ph)PDLHITPIYEGR_
PKP4 Phosphorylation S314 0.714 0.627 _VGS(ph)PLTLTDAQTR_
PKP4 Phosphorylation S447 0.245 0.506 _TGS(ph)VGIGNLQR_
PKP4 Phosphorylation S276 -0.230 0.429 _AAS(ph)PYS(ph)QRPASPTAIR_
PKP4 Phosphorylation S336 0.308 0.260 _VASPSQGQVGSS(ph)SPKR_
PKP4 Phosphorylation S281 0.155 0.243 _AAS(ph)PYSQRPAS(ph)PTAIR_
PKP4 Phosphorylation S327 0.346 0.137 _VAS(ph)PSQGQVGS(ph)SSPK_
PKP4 Phosphorylation S75 0.390 -0.006 _LGAES(ph)PSIASTSSTEK_
PKP4 Phosphorylation S337 0.059 -0.044 _VAS(ph)PSQGQVGSSS(ph)PK_
PKP4 Phosphorylation S231 -0.562 -0.103 _AQS(ph)PSYVISTGVS(ph)PSR_
PKP4 Phosphorylation S273 -0.230 -0.252 _AAS(ph)PYSQRPAS(ph)PTAIR_
PKP4 Phosphorylation S221 -0.272 -0.602 _AQS(ph)PSYVISTGVS(ph)PSR_
PKP4 Ubiquitylation K518 -1.745 -1.024 _SPSIDSIQK(gl)DPR_
PKP4 Phosphorylation S403 0.501 _TGS(ph)GIGNLQR_

Background Information for PKP4:


Pubmed-PKP4 »
Uniprot-PKP4 »
Biogrid-PKP4 »
ProteomicsDB-PKP4 »

Tumorportal-PKP4 »
COSMIC-PKP4 »
GenomeRNAi-PKP4 »
Genecards-PKP4


Protein-protein Interactions for PKP4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKAP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait EVPL Cat. description Hein, Mann, Cell 2015
Category members IP bait FERMT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait USP7 Cat. description Hein, Mann, Cell 2015
Category members IP bait APBA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C12orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf54 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTNNA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGFR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAVCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNJ5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TACR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PKP4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Armadillo IPR000225 1.58


Protein complexes (CORUM database) featuring PKP4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PKP4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0032467 positive regulation of cytokinesis Database 0.35
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0007043 cell-cell junction assembly Database 0.31
Category members GO Category GO:0030057 desmosome Database 0.26
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030155 regulation of cell adhesion Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0
Category members GO Category GO:0044291 cell-cell contact zone Database 0
Category members GO Category GO:0051233 spindle midzone Database 0


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