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Query: PIP5K1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PIP5K1A 0 0.522 0.290 -0.670 0.831
PIP5K1A 0 0.522 0.290 -0.670 0.249 -0.303 -1.270
PIP5K1A 0 0.522 1.090 -0.930 0.831
PIP5K1A 0 0.522 1.090 -0.930 0.249 -0.303 -1.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PIP5K1A Ubiquitylation K78 0.181 _SVDSSGETTYK(gl)K_
PIP5K1A Ubiquitylation K79 0.181 _SVDSSGETTYK(gl)K_
PIP5K1A Phosphorylation S475 -0.061 0.135 _RAGS(ph)SGNSCITYQPSVSGEHK_
PIP5K1A Phosphorylation S458 -1.008 _KIPLKPS(ph)PSK_
PIP5K1A Phosphorylation S460 -1.118 _KIPLKPSPS(ph)K_
PIP5K1A Ubiquitylation K103 -0.225 -2.556 _GAIQLGITHTVGSLSTK(gl)PER_
PIP5K1A Ubiquitylation K223 -0.376 _EK(gl)PLPTFK_
PIP5K1A Phosphorylation S476 0.621 _RAGSS(ph)GNSCITYQPSVSGEHK_

Background Information for PIP5K1A:


Pubmed-PIP5K1A »
Uniprot-PIP5K1A »
Biogrid-PIP5K1A »
ProteomicsDB-PIP5K1A »

Tumorportal-PIP5K1A »
COSMIC-PIP5K1A »
GenomeRNAi-PIP5K1A »
Genecards-PIP5K1A


Protein-protein Interactions for PIP5K1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait AHCYL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGAP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARIH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMK2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GFOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IMPDH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCTD17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP5K1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGGTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF323 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PIP5K1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PInositol-4-P-5-kinase_core IPR002498 0
Category members PInositol-4P-5-kinase_core_sub IPR016034 0


Protein complexes (CORUM database) featuring PIP5K1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PIP5K1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members Pathway Pathway_670 PID_ARF_3PATHWAY 0 3.15
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_611 PID_ECADHERIN_KERATINOCYTE_PATHWAY 0 1.34
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members GO Category GO:0032587 ruffle membrane Database 0.65
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0016310 phosphorylation Database 0.21
Category members GO Category GO:0005847 mRNA cleavage and polyadenylation specificity factor complex Database 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members GO Category GO:0048041 focal adhesion assembly Database 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_296 PID_ARF6_DOWNSTREAM_PATHWAY 0 0.08
Category members GO Category GO:0006909 phagocytosis Database 0.08
Category members GO Category GO:0006650 glycerophospholipid metabolic process Database 0.07
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members Pathway Pathway_564 PID_AVB3_OPN_PATHWAY 0 0
Category members Pathway Pathway_668 PID_RHOA_PATHWAY 0 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008654 phospholipid biosynthetic process Database 0
Category members GO Category GO:0010761 fibroblast migration Database 0
Category members GO Category GO:0016307 phosphatidylinositol phosphate kinase activity Database 0
Category members GO Category GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0032863 activation of Rac GTPase activity Database 0
Category members GO Category GO:0046488 phosphatidylinositol metabolic process Database 0
Category members GO Category GO:0060326 cell chemotaxis Database 0


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