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Query: PES1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PES1 0 0.091 0.000 0.210 -1.535 -0.358

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PES1 Ubiquitylation K533 0.504 1.270 _LAQEEESEAK(gl)R_
PES1 Ubiquitylation K98 -0.002 _AYGK(gl)SEWNTVER_

Background Information for PES1:


Pubmed-PES1 »
Uniprot-PES1 »
Biogrid-PES1 »
ProteomicsDB-PES1 »

Tumorportal-PES1 »
COSMIC-PES1 »
GenomeRNAi-PES1 »
Genecards-PES1


Protein-protein Interactions for PES1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INPP5K Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PES1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members BRCT_dom IPR001357 1.59


Protein complexes (CORUM database) featuring PES1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PES1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members GO Category GO:0000793 condensed chromosome Database 1.32
Category members GO Category GO:0042273 ribosomal large subunit biogenesis Database 0.59
Category members GO Category GO:0042254 ribosome biogenesis Database 0.29
Category members GO Category GO:0007000 nucleolus organization Database 0.18
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Database 0.1
Category members GO Category GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Database 0.1
Category members GO Category GO:0030687 preribosome, large subunit precursor Database 0.1
Category members GO Category GO:0070545 PeBoW complex Database 0.1
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0033365 protein localization to organelle Database 0
Category members GO Category GO:0043021 ribonucleoprotein complex binding Database 0


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