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Query: PDIA4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDIA4 1 4.589 -0.040 -0.150 0.422 0.500 0.333

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDIA4 Ubiquitylation K141 2.398 _FDVSGYPTIK(gl)ILK_
PDIA4 Ubiquitylation K245 0.936 1.890 _VDATAETDLAK(gl)R_
PDIA4 Ubiquitylation K163 0.009 _TQEEIVAK(gl)VR_

Background Information for PDIA4:





Protein-protein Interactions for PDIA4

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait PDIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM111 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDIA4

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Disulphide_isomerase IPR005788 1.41
Category members Thioredoxin_domain IPR013766 0.49
Category members Prot_disulphide_isomerase IPR005792 0.42
Category members Calsequestrin IPR001393 0.3
Category members Thioredoxin-like_fold IPR012336 0.16


Protein complexes (CORUM database) featuring PDIA4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PDIA4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0003756 protein disulfide isomerase activity Database 1.21
Category members GO Category GO:0006662 glycerol ether metabolic process Database 0.79
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_187 KEGG_VIBRIO_CHOLERAE_INFECTION 0 0.44
Category members GO Category GO:0016853 isomerase activity Database 0.37
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0045454 cell redox homeostasis Database 0.05
Category members GO Category GO:0009306 protein secretion Database 0.02
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0015035 protein disulfide oxidoreductase activity Database 0


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