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bioLOGIC Data

Query: PARVA

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
PARVA	0	0.994	-0.710	1.020

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
PARVA	Phosphorylation	T3	-0.031	0.005	_(ac)AT(ph)SPQKS(ph)PSVPK_
PARVA	Phosphorylation	S4	-0.031	0.005	_(ac)ATS(ph)PQKS(ph)PSVPK_
PARVA	Phosphorylation	S14	-0.492	-0.182	_SPSVPKS(ph)PTPK_
PARVA	Phosphorylation	S8	-0.343	-0.395	_(ac)AT(ph)SPQKS(ph)PSVPK_
PARVA	Phosphorylation	T16		-0.703	_SPT(ph)PKSPPSR_
PARVA	Phosphorylation	S19	-0.513	-0.721	_SPTPKS(ph)PPSR_
PARVA	Phosphorylation	S10	-1.421	-1.107	_SPS(ph)VPKSPTPK_

Background Information for PARVA:

Pubmed-PARVA »

Uniprot-PARVA »

Biogrid-PARVA »

ProteomicsDB-PARVA »

Tumorportal-PARVA »

COSMIC-PARVA »

GenomeRNAi-PARVA »

Genecards-PARVA

Protein-protein Interactions for PARVA

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ILK	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait LIMS1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait LPXN	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PARVA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RSU1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in PARVA

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	CH-domain	IPR001715	0.63

Protein complexes (CORUM database) featuring PARVA

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring PARVA

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0003779	actin binding	Database	5.41
Category members	GO Category	GO:0015629	actin cytoskeleton	Database	2.22
Category members	GO Category	GO:0030027	lamellipodium	Database	1.77
Category members	Pathway	Pathway_924	PID_ILK_PATHWAY	0	1.75
Category members	GO Category	GO:0005886	plasma membrane	Database	1.21
Category members	Pathway	Pathway_595	KEGG_FOCAL_ADHESION	0	1.08
Category members	GO Category	GO:0007163	establishment or maintenance of cell polarity	Database	1.08
Category members	GO Category	GO:0005925	focal adhesion	Database	0.68
Category members	GO Category	GO:0030018	Z disc	Database	0.32
Category members	GO Category	GO:0031532	actin cytoskeleton reorganization	Database	0.29
Category members	GO Category	GO:0034329	cell junction assembly	Database	0.29
Category members	GO Category	GO:0034446	substrate adhesion-dependent cell spreading	Database	0.26
Category members	Pathway	Pathway_560	REACTOME_CELL_CELL_COMMUNICATION	0	0.25
Category members	Pathway	Pathway_923	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	0	0.18
Category members	GO Category	GO:0003148	outflow tract septum morphogenesis	Database	0.13
Category members	GO Category	GO:0002040	sprouting angiogenesis	Database	0.12
Category members	Pathway	Pathway_925	REACTOME_CELL_JUNCTION_ORGANIZATION	0	0
Category members	GO Category	GO:0007155	cell adhesion	Database	0
Category members	GO Category	GO:0008360	regulation of cell shape	Database	0
Category members	GO Category	GO:0034113	heterotypic cell-cell adhesion	Database	0
Category members	GO Category	GO:0060271	cilium morphogenesis	Database	0