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bioLOGIC Data

Query: PARD6B

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
PARD6B	0	3.058	-1.070	1.470

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
PARD6B	Phosphorylation	S11	0.746	0.842	_HGAGS(ph)GCLGTM(ox)EVK_

Background Information for PARD6B:

Pubmed-PARD6B »

Uniprot-PARD6B »

Biogrid-PARD6B »

ProteomicsDB-PARD6B »

Tumorportal-PARD6B »

COSMIC-PARD6B »

GenomeRNAi-PARD6B »

Genecards-PARD6B

Protein-protein Interactions for PARD6B

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait LLGL1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait LLGL2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PARD6A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PARD6B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PRKCI	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RHOJ	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in PARD6B

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	PDZ	IPR001478	0.15
Category members	OPR_PB1	IPR000270	0

Protein complexes (CORUM database) featuring PARD6B

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	956	PAR-3-PAR-6B-PRKCI complex	Database	0.52
Category members	Corum	955	LLGL2-PAR-6B-PRKCI complex	Database	0.32
Category members	Corum	959	LLGL1-PAR-6B-PRKCI complex	Database	0.01
Category members	Corum	5558	PAR6-CDC42 complex	Database	0

Categories featuring PARD6B

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0043234	protein complex	Database	2.73
Category members	GO Category	GO:0005938	cell cortex	Database	2.26
Category members	Pathway	Pathway_413	KEGG_TIGHT_JUNCTION	0	2.08
Category members	Pathway	Pathway_666	KEGG_ENDOCYTOSIS	0	1.25
Category members	GO Category	GO:0005886	plasma membrane	Database	1.21
Category members	GO Category	GO:0051301	cell division	Database	1.15
Category members	GO Category	GO:0007163	establishment or maintenance of cell polarity	Database	1.08
Category members	GO Category	GO:0005923	tight junction	Database	0.69
Category members	GO Category	GO:0007049	cell cycle	Database	0.69
Category members	GO Category	GO:0030334	regulation of cell migration	Database	0.61
Category members	GO Category	GO:0006461	protein complex assembly	Database	0.57
Category members	GO Category	GO:0070830	tight junction assembly	Database	0.36
Category members	GO Category	GO:0007043	cell-cell junction assembly	Database	0.31
Category members	GO Category	GO:0034329	cell junction assembly	Database	0.29
Category members	Pathway	Pathway_560	REACTOME_CELL_CELL_COMMUNICATION	0	0.25
Category members	GO Category	GO:0007409	axonogenesis	Database	0.13
Category members	GO Category	GO:0045216	cell-cell junction organization	Database	0.1
Category members	Pathway	Pathway_1236	REACTOME_TIGHT_JUNCTION_INTERACTIONS	0	0
Category members	Pathway	Pathway_1237	REACTOME_CELL_CELL_JUNCTION_ORGANIZATION	0	0
Category members	Pathway	Pathway_925	REACTOME_CELL_JUNCTION_ORGANIZATION	0	0
Category members	GO Category	GO:0045177	apical part of cell	Database	0