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Query: OTUD7B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OTUD7B 0 2.804

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OTUD7B Ubiquitylation K93 0.152 0.969 _QDDIVQEK(gl)R_
OTUD7B Phosphorylation S100 0.815 0.868 _GIS(ph)HASSSIVSLAR_
OTUD7B Ubiquitylation K644 0.103 0.509 _FLAEQK(gl)QK_
OTUD7B Phosphorylation S449 -0.896 _WIPLSSDAQAPLAQPES(ph)PTASAGDEPR_

Background Information for OTUD7B:





Protein-protein Interactions for OTUD7B

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OTUD7B

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring OTUD7B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OTUD7B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0071108 protein K48-linked deubiquitination Database 0.88
Category members GO Category GO:0070530 K63-linked polyubiquitin binding Database 0.35
Category members GO Category GO:0070536 protein K63-linked deubiquitination Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0035871 protein K11-linked deubiquitination Database 0
Category members GO Category GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling Database 0


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