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Query: OCLN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OCLN 0 2.205 1.360 -0.180
OCLN 0 2.205 1.360 -0.180 0.052 0.302

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OCLN Phosphorylation S408 1.405 _RTEQDHYETDYTTGGES(ph)CDELEEDWIR_
OCLN Phosphorylation S358 0.095 0.535 _STPVPEVVQELPLTS(ph)PVDDFR_
OCLN Phosphorylation T357 0.065 0.472 _STPVPEVVQELPLT(ph)SPVDDFR_
OCLN Ubiquitylation K379 -0.036 0.238 _YSSGGNFETPSK(gl)R_
OCLN Phosphorylation S370 0.069 0.114 _YSS(ph)GGNFETPSK_
OCLN Phosphorylation S341 -0.395 -0.095 _RFYPESS(ph)YK_
OCLN Ubiquitylation K330 -0.208 -0.513 _VDSPMAYSSNGK(gl)VNDKR_
OCLN Phosphorylation T376 -1.372 -1.062 _YSSGGNFET(ph)PSK_
OCLN Ubiquitylation K488 0.113 _LKQVK(gl)GSADYK_

Background Information for OCLN:


Pubmed-OCLN »
Uniprot-OCLN »
Biogrid-OCLN »
ProteomicsDB-OCLN »

Tumorportal-OCLN »
COSMIC-OCLN »
GenomeRNAi-OCLN »
Genecards-OCLN


Protein-protein Interactions for OCLN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C19orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IGSF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OCLN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFSF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OCLN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Marvel IPR008253 0
Category members Occludin_RNApol2_elong_fac_ELL IPR010844 0


Protein complexes (CORUM database) featuring OCLN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OCLN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members Pathway Pathway_877 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0046498 S-adenosylhomocysteine metabolic process Database 0.62
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members Pathway Pathway_1019 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS 0 0.17
Category members GO Category GO:0045216 cell-cell junction organization Database 0.1
Category members GO Category GO:0016327 apicolateral plasma membrane Database 0.04
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members GO Category GO:0008119 thiopurine S-methyltransferase activity Database 0
Category members GO Category GO:0008757 S-adenosylmethionine-dependent methyltransferase activity Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0030139 endocytic vesicle Database 0
Category members GO Category GO:0046500 S-adenosylmethionine metabolic process Database 0


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