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Query: OBSCN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OBSCN 0 2.154 -0.680 0.510
OBSCN 0 2.154 -0.170 0.030
OBSCN 0 2.154 1.520 -0.830

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OBSCN Phosphorylation S1485 1.190 _LSFS(ph)SKVR_
OBSCN Phosphorylation S1486 0.964 1.070 _LSFSS(ph)KVR_

Background Information for OBSCN:


Pubmed-OBSCN »
Uniprot-OBSCN »
Biogrid-OBSCN »
ProteomicsDB-OBSCN »

Tumorportal-OBSCN »
COSMIC-OBSCN »
GenomeRNAi-OBSCN »
Genecards-OBSCN


Protein-protein Interactions for OBSCN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait C10orf12 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait HSF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1107 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNA Cat. description Hein, Mann, Cell 2015
Category members IP bait RPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS18 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS28 Cat. description Hein, Mann, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OBSCN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Fibronectin_type3 IPR003961 0.19
Category members PH_domain IPR001849 0.14
Category members Ig_I-set IPR013098 0.13
Category members Ig_V-set IPR013106 0.09
Category members DH-domain IPR000219 0.05
Category members Kinase-like_dom IPR011009 0.03
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members SH3_domain IPR001452 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Ig_V-set_subgr IPR003596 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring OBSCN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OBSCN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0030018 Z disc Database 0.32
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0008307 structural constituent of muscle Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030016 myofibril Database 0
Category members GO Category GO:0030506 ankyrin binding Database 0
Category members GO Category GO:0031430 M band Database 0
Category members GO Category GO:0031432 titin binding Database 0
Category members GO Category GO:0036309 protein localization to M-band Database 0
Category members GO Category GO:0045214 sarcomere organization Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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