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Query: NLGN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NLGN2 0 0.318 0.140 0.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NLGN2 Ubiquitylation K748 0.088 _ELPPEEELVSLQLK(gl)R_

Background Information for NLGN2:


Pubmed-NLGN2 »
Uniprot-NLGN2 »
Biogrid-NLGN2 »
ProteomicsDB-NLGN2 »

Tumorportal-NLGN2 »
COSMIC-NLGN2 »
GenomeRNAi-NLGN2 »
Genecards-NLGN2


Protein-protein Interactions for NLGN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait B3GAT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRISP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NLGN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NLGN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Neuroligin IPR000460 0
Category members CarbesteraseB IPR002018 0
Category members AB_hydrolase_3 IPR013094 0
Category members AB_hydrolase IPR029058 0


Protein complexes (CORUM database) featuring NLGN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NLGN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0060077 inhibitory synapse Database 0.11
Category members GO Category GO:0050808 synapse organization Database 0.08
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0050804 regulation of synaptic transmission Database 0.05
Category members GO Category GO:0019233 sensory perception of pain Database 0.05
Category members GO Category GO:0035641 locomotory exploration behavior Database 0.04
Category members GO Category GO:0050885 neuromuscular process controlling balance Database 0.02
Category members GO Category GO:0032230 positive regulation of synaptic transmission, GABAergic Database 0.01
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members GO Category GO:0002087 regulation of respiratory gaseous exchange by neurological system process Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0007158 neuron cell-cell adhesion Database 0
Category members GO Category GO:0007416 synapse assembly Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0035418 protein localization to synapse Database 0
Category members GO Category GO:0042043 neurexin family protein binding Database 0
Category members GO Category GO:0042734 presynaptic membrane Database 0
Category members GO Category GO:0045217 cell-cell junction maintenance Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0
Category members GO Category GO:0051965 positive regulation of synapse assembly Database 0
Category members GO Category GO:0051968 positive regulation of synaptic transmission, glutamatergic Database 0


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