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Query: NKAP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NKAP 1 1.377 1.470 -1.040 -0.400 -0.272 -0.498

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NKAP Phosphorylation S64 2.600 _NGLTHQLGGLS(ph)QGSR_
NKAP Phosphorylation S9 0.004 _APVSGSRS(ph)PDREASGSGGR_
NKAP Phosphorylation S149 -0.075 -0.248 _IGELGAPEVWGLS(ph)PK_
NKAP Ubiquitylation K379 0.022 _ENQIYSADEK(gl)R_

Background Information for NKAP:





Protein-protein Interactions for NKAP

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait UPF3B Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP17A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LLGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF40A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNCRIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCCHC17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NKAP

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DUF926 IPR009269 0


Protein complexes (CORUM database) featuring NKAP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NKAP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0019827 stem cell maintenance Database 0.48
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0033077 T cell differentiation in thymus Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0030851 granulocyte differentiation Database 0
Category members GO Category GO:0031490 chromatin DNA binding Database 0
Category members GO Category GO:0046638 positive regulation of alpha-beta T cell differentiation Database 0
Category members GO Category GO:0071425 hematopoietic stem cell proliferation Database 0


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