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Query: NEIL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NEIL3 1 -0.197 2.830 -1.410

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NEIL3 Ubiquitylation K291 -0.197 _ENPQHVDICK(gl)LPTR_
NEIL3 Ubiquitylation K13 -1.903 _VEGPGCTLNGEK(gl)IR_

Background Information for NEIL3:


Pubmed-NEIL3 »
Uniprot-NEIL3 »
Biogrid-NEIL3 »
ProteomicsDB-NEIL3 »

Tumorportal-NEIL3 »
COSMIC-NEIL3 »
GenomeRNAi-NEIL3 »
Genecards-NEIL3


Protein-protein Interactions for NEIL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ECT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEIL3 Cat. description Hein, Mann, Cell 2015


Protein Domains in NEIL3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RanBP2 IPR001876 0.18
Category members Znf_DNA_glyclase/AP_lyase IPR000214 0
Category members Znf_GRF IPR010666 0
Category members Ribosomal_S13-like_H2TH IPR010979 0
Category members DNA_glycosylase/AP_lyase_cat IPR012319 0
Category members DNA_glyclase/AP_lyase_DNA-bd IPR015886 0


Protein complexes (CORUM database) featuring NEIL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NEIL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0006289 nucleotide-excision repair Database 6.65
Category members GO Category GO:0003684 damaged DNA binding Database 4.54
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0000405 bubble DNA binding Database 0.4
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity Database 0.16
Category members GO Category GO:0006284 base-excision repair Database 0.04
Category members Pathway Pathway_334 KEGG_BASE_EXCISION_REPAIR 0 0
Category members GO Category GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds Database 0
Category members GO Category GO:0019104 DNA N-glycosylase activity Database 0


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