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Query: NDUFA8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NDUFA8 1 0.586 0.870 -0.830 -0.305 -0.739 -0.548

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NDUFA8 Ubiquitylation K65 0.281 1.896 _LVNK(gl)CALDFFR_
NDUFA8 Ubiquitylation K106 -0.122 _KQQAK(gl)FDECVLDK_

Background Information for NDUFA8:


Pubmed-NDUFA8 »
Uniprot-NDUFA8 »
Biogrid-NDUFA8 »
ProteomicsDB-NDUFA8 »

Tumorportal-NDUFA8 »
COSMIC-NDUFA8 »
GenomeRNAi-NDUFA8 »
Genecards-NDUFA8


Protein-protein Interactions for NDUFA8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATM Cat. description Hein, Mann, Cell 2015
Category members IP bait CNTROB Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait ECSIT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NDUFA8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CHCH IPR010625 0


Protein complexes (CORUM database) featuring NDUFA8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NDUFA8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005758 mitochondrial intermembrane space Database 0.33
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0008137 NADH dehydrogenase (ubiquinone) activity Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members GO Category GO:0005747 mitochondrial respiratory chain complex I Database 0.08
Category members GO Category GO:0006120 mitochondrial electron transport, NADH to ubiquinone Database 0.07
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0


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