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Query: MYO9B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYO9B 2 3.635 0.820 -0.550

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYO9B Phosphorylation S1405 1.890 1.745 _KKPGDASSLPDAGLS(ph)PGSQVDSK_
MYO9B Phosphorylation S1354 0.955 0.892 _RTS(ph)FSTSDVSK_
MYO9B Phosphorylation S1290 0.761 0.703 _VQEKPDS(ph)PGGSTQIQR_
MYO9B Phosphorylation S717 0.375 _AAGMSS(ph)PGAQSHPEELPR_
MYO9B Phosphorylation S1992 -0.221 0.324 _GS(ph)DEENLDSETSASTESLLEER_
MYO9B Phosphorylation S1267 -0.114 -0.387 _VSPPAPGS(ph)APET(ph)PEDK_
MYO9B Phosphorylation T1271 -0.114 -0.387 _VSPPAPGS(ph)APET(ph)PEDK_
MYO9B Phosphorylation S1261 -1.739 -2.057 _VS(ph)PPAPGSAPETPEDK_

Background Information for MYO9B:





Protein-protein Interactions for MYO9B

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf179 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DQX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EID1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM131B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEUROG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYO9B

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members PE/DAG-bd IPR002219 0.63
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members Myosin_head_motor_dom IPR001609 0.17
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Ras-assoc IPR000159 0
Category members RhoGAP_dom IPR000198 0


Protein complexes (CORUM database) featuring MYO9B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYO9B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0030010 establishment of cell polarity Database 0.91
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0030898 actin-dependent ATPase activity Database 0.31
Category members GO Category GO:0043008 ATP-dependent protein binding Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030048 actin filament-based movement Database 0.28
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members GO Category GO:0000146 microfilament motor activity Database 0.27
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0043547 positive regulation of GTPase activity Database 0.21
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005884 actin filament Database 0.08
Category members GO Category GO:0032433 filopodium tip Database 0.01
Category members GO Category GO:0031941 filamentous actin Database 0.01
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0002548 monocyte chemotaxis Database 0
Category members GO Category GO:0005100 Rho GTPase activator activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048246 macrophage chemotaxis Database 0


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