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Query: MXD4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MXD4 0 1.246 1.700 -1.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MXD4 Ubiquitylation K152 1.246 _HTTLSLLK(gl)R_
MXD4 Ubiquitylation K172 0.992 _ALSIK(gl)EQLQQEHR_
MXD4 Ubiquitylation K99 -0.274 _TK(gl)AAGLVR_

Background Information for MXD4:


Pubmed-MXD4 »
Uniprot-MXD4 »
Biogrid-MXD4 »
ProteomicsDB-MXD4 »

Tumorportal-MXD4 »
COSMIC-MXD4 »
GenomeRNAi-MXD4 »
Genecards-MXD4


Protein-protein Interactions for MXD4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait TRAPPC11 Cat. description Hein, Mann, Cell 2015


Protein Domains in MXD4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members bHLH_dom IPR011598 0.32


Protein complexes (CORUM database) featuring MXD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MXD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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