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Query: MED26

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MED26 1 1.574 0.500 -1.120

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MED26 Phosphorylation S447 -0.042 _EPVRADS(ph)PVHMEQQSR_
MED26 Phosphorylation S7 -0.245 -0.270 _(ac)TAAPAS(ph)PQQIR_
MED26 Phosphorylation S361 1.616 _AGLS(ph)PAEPLLSR_

Background Information for MED26:





Protein-protein Interactions for MED26

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MASTL Cat. description Hein, Mann, Cell 2015
Category members IP bait MED22 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait MED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2G Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MED26

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TFIIS/CRSP70_N_sub IPR003617 0.13
Category members TFIIS_N IPR017923 0.01


Protein complexes (CORUM database) featuring MED26

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 230 Mediator complex Database 0.76
Category members Corum 5450 Mediator complex Database 0.45
Category members Corum 909 ARC92-Mediator complex Database 0.13
Category members Corum 548 DRIP complex Database 0.08
Category members Corum 549 DRIP complex Database 0.08
Category members Corum 232 ARC complex Database 0.05
Category members Corum 217 CRSP complex Database 0
Category members Corum 218 CRSP complex Database 0
Category members Corum 284 CRSP complex Database 0
Category members Corum 288 ARC complex Database 0


Categories featuring MED26

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0016592 mediator complex Database 0.53
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0


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