bioLOGIC-db

bioLOGIC Data

Query: MED10

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
MED10	0	-0.375

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
MED10	Ubiquitylation	K53	-0.830	0.455	_LNFIVTGLQDIDK(gl)CR_
MED10	Ubiquitylation	K91		0.241	_ALAK(gl)NEQVK_
MED10	Ubiquitylation	K106		0.002	_FK(gl)SLLIQELSK_
MED10	Ubiquitylation	K82	-1.856	-0.301	_NPQLYTK(gl)ECLER_
MED10	Ubiquitylation	K4	-1.822	-1.288	_(ac)AEK(gl)FDHLEEHLEK_
MED10	Ubiquitylation	K98	-1.357		_GK(gl)IDTMKK_
MED10	Ubiquitylation	K104	-0.971		_GKIDTMKK(gl)_

ProteomicsDB-MED10 »

Protein-protein Interactions for MED10

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CDK8	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CHMP4C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MED12	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MED22	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NCAPH	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NEDD1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RPL35	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait BIRC5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CCNC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CDK19	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CDK8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED18	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED19	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED21	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TCL1B	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in MED10

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring MED10

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	230	Mediator complex	Database	0.76
Category members	Corum	535	TRAP complex	Database	0.76
Category members	Corum	300	PC2 complex	Database	0.53
Category members	Corum	5450	Mediator complex	Database	0.45
Category members	Corum	301	SMCC complex	Database	0.45
Category members	Corum	229	NAT complex	Database	0

Categories featuring MED10

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005654	nucleoplasm	Database	INF
Category members	GO Category	GO:0010467	gene expression	Database	INF
Category members	Pathway	Pathway_90	REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION	0	0.88
Category members	GO Category	GO:0016592	mediator complex	Database	0.53
Category members	GO Category	GO:0019827	stem cell maintenance	Database	0.48
Category members	Pathway	Pathway_41	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	0	0.35
Category members	Pathway	Pathway_42	REACTOME_DEVELOPMENTAL_BIOLOGY	0	0.32
Category members	GO Category	GO:0006367	transcription initiation from RNA polymerase II promoter	Database	0.25
Category members	Pathway	Pathway_1	REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM	0	0.23
Category members	GO Category	GO:0006357	regulation of transcription from RNA polymerase II promoter	Database	0.19
Category members	GO Category	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Database	0.13
Category members	Pathway	Pathway_822	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	0	0.09
Category members	GO Category	GO:0001104	RNA polymerase II transcription cofactor activity	Database	0.08
Category members	Pathway	Pathway_4	REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS	0	0