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Query: MATR3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MATR3 2 4.283 0.330 -0.770 -0.059 -2.461 -1.002
MATR3 2 4.283 0.330 -0.770 0.616 -1.792 -0.824 -0.795 -0.093

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MATR3 Phosphorylation T612 2.910 2.961 _T(ph)DGSQKTESSTEGKEQEEK_
MATR3 Phosphorylation S208 3.082 2.840 _S(ph)QESGYYDR_
MATR3 Phosphorylation S615 2.286 2.251 _TDGS(ph)QKTESSTEGKEQEEK_
MATR3 Phosphorylation S206 -0.408 2.048 _GPSLNPVLDYDHGS(ph)R_
MATR3 Phosphorylation S9 1.062 1.758 _SFQQSS(ph)LSR_
MATR3 Phosphorylation S211 1.684 _DSFDDRGPSLNPVLDYDHGSRSQES(ph)GYYDR_
MATR3 Phosphorylation S621 2.639 1.672 _TDGSQKTESS(ph)TEGKEQEEK_
MATR3 Phosphorylation S604 1.224 1.629 _SYS(ph)PDGKES(ph)PSDK_
MATR3 Phosphorylation T150 1.273 _RRT(ph)EEGPTLSYGR_
MATR3 Ubiquitylation K181 0.418 0.703 _DDWEEK(gl)R_
MATR3 Ubiquitylation K555 0.016 0.639 _K(gl)ALWFQGR_
MATR3 Phosphorylation S195 0.999 0.590 _RDSFDDRGPS(ph)LNPVLDYDHGSR_
MATR3 Ubiquitylation K884 0.657 0.492 _FLNK(gl)LAEERR_
MATR3 Phosphorylation S596 -0.031 0.457 _RS(ph)YSPDGK_
MATR3 Ubiquitylation K491 -0.193 0.356 _FDQK(gl)QELGR_
MATR3 Phosphorylation S188 0.552 0.352 _RDS(ph)FDDR_
MATR3 Ubiquitylation K588 -0.137 0.306 _GIDLLK(gl)K_
MATR3 Ubiquitylation K589 0.306 _GIDLLK(gl)K_
MATR3 Phosphorylation S598 0.251 0.233 _SYS(ph)PDGKESPSDK_
MATR3 Ubiquitylation K554 -0.121 0.185 _EDAMAMVDHCLK(gl)K_
MATR3 Ubiquitylation K3 -0.669 -0.130 _(ac)SK(gl)SFQQSSLSR_
MATR3 Ubiquitylation K522 -1.136 -0.691 _LAEPYGK(gl)IK_
MATR3 Phosphorylation S164 -0.799 -0.754 _S(ph)ATREPPYR_
MATR3 Phosphorylation S814 -1.235 _NEENTEPGAESSENADDPNKDTSENADGQS(ph)DENKDDYTIPDEYR_
MATR3 Ubiquitylation K524 -0.770 _LAEPYGKIK(gl)_
MATR3 Ubiquitylation K565 0.765 _CVK(gl)VDLSEK_
MATR3 Ubiquitylation K571 0.335 _VDLSEK(gl)YK_
MATR3 Ubiquitylation K880 1.094 _LKK(gl)FLNK_

Background Information for MATR3:


Pubmed-MATR3 »
Uniprot-MATR3 »
Biogrid-MATR3 »
ProteomicsDB-MATR3 »

Tumorportal-MATR3 »
COSMIC-MATR3 »
GenomeRNAi-MATR3 »
Genecards-MATR3


Protein-protein Interactions for MATR3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKAP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SET Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK5RAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MATR3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Znf_C2H2_matrin IPR000690 0
Category members Znf_U1 IPR003604 0


Protein complexes (CORUM database) featuring MATR3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1335 SNW1 complex Database 3.59
Category members Corum 335 p54(nrb)-PSF-matrin3 complex Database 0.17


Categories featuring MATR3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005637 nuclear inner membrane Database 1.98
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members Disease phenotype Amyotrophic_lateral_sclerosis Amyotrophic lateral sclerosis Database 0.21


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