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Query: MARK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MARK1 0 -3.178 -1.135

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MARK1 Phosphorylation S403 -1.363 -0.680 _SRPSSDLNNSTLQS(ph)PAHLK_

Background Information for MARK1:


Pubmed-MARK1 »
Uniprot-MARK1 »
Biogrid-MARK1 »
ProteomicsDB-MARK1 »

Tumorportal-MARK1 »
COSMIC-MARK1 »
GenomeRNAi-MARK1 »
Genecards-MARK1


Protein-protein Interactions for MARK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC20 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDH19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COL4A3BP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MARK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members Kinase-like_dom IPR011009 0.03
Category members KA1/Ssp2_C IPR028375 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members KA1_dom IPR001772 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MARK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MARK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0070300 phosphatidic acid binding Database 0.19
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Database 0.09
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0050321 tau-protein kinase activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0001786 phosphatidylserine binding Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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