bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: MAP4K4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAP4K4 0 1.597 -0.500 0.030
MAP4K4 0 1.597 -0.500 0.030 0.038 0.092 0.062

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAP4K4 Phosphorylation S708 0.247 0.386 _TTSRS(ph)PVLSR_
MAP4K4 Phosphorylation S706 0.353 0.381 _TTS(ph)RSPVLSR_
MAP4K4 Phosphorylation T704 0.480 0.190 _T(ph)TSRSPVLSR_
MAP4K4 Phosphorylation S716 0.989 -0.508 _RDS(ph)PLQGSGQQNSQAGQR_
MAP4K4 Phosphorylation S981 -0.167 -1.787 _KGS(ph)VVNVNPTNTRPQSDTPEIR_

Background Information for MAP4K4:


Pubmed-MAP4K4 »
Uniprot-MAP4K4 »
Biogrid-MAP4K4 »
ProteomicsDB-MAP4K4 »

Tumorportal-MAP4K4 »
COSMIC-MAP4K4 »
GenomeRNAi-MAP4K4 »
Genecards-MAP4K4


Protein-protein Interactions for MAP4K4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FGFR1OP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait RNH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATG14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C2orf29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEPACAM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NANOS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAP2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX264 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAP4K4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Citron IPR001180 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAP4K4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAP4K4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0046328 regulation of JNK cascade Database 0.22
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_629 PID_EPHB_FWD_PATHWAY 0 0.14
Category members GO Category GO:0004702 receptor signaling protein serine/threonine kinase activity Database 0.1
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_734 PID_CERAMIDE_PATHWAY 0 0
Category members Pathway Pathway_738 PID_TNF_PATHWAY 0 0
Category members GO Category GO:0005083 small GTPase regulator activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


.

© Copyright Svejstrup Laboratory 2015