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Query: KIF4A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF4A 2 5.962 0.450 -0.410 0.413
KIF4A 2 5.962 0.450 -0.410 -0.346 -0.337

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF4A Phosphorylation S1228 1.720 2.072 _RALASNTSFFSGCS(ph)PIEEEAH_
KIF4A Ubiquitylation K715 0.852 1.337 _LK(gl)DALQK_
KIF4A Phosphorylation S804 1.144 0.733 _TFS(ph)LTEVR_
KIF4A Phosphorylation T820 0.302 0.224 _GQVSESEDSIT(ph)K_
KIF4A Phosphorylation T1184 -1.056 _T(ph)PPAPSPFDLPELK_
KIF4A Ubiquitylation K613 1.103 _LQELEGQIADLK(gl)K_
KIF4A Ubiquitylation K614 1.103 _LQELEGQIADLK(gl)K_
KIF4A Ubiquitylation K883 -0.435 _IQVSK(gl)LESSLK_
KIF4A Ubiquitylation K993 0.075 _QK(gl)LTLLQVASR_
KIF4A Phosphorylation T802 1.153 _RT(ph)FSLTEVR_
KIF4A Phosphorylation S818 -0.103 _GQVSESEDS(ph)ITK_

Background Information for KIF4A:


Pubmed-KIF4A »
Uniprot-KIF4A »
Biogrid-KIF4A »
ProteomicsDB-KIF4A »

Tumorportal-KIF4A »
COSMIC-KIF4A »
GenomeRNAi-KIF4A »
Genecards-KIF4A


Protein-protein Interactions for KIF4A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF4A Cat. description Hein, Mann, Cell 2015
Category members IP bait C9orf68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF4A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Kinesin_motor_dom IPR001752 0


Protein complexes (CORUM database) featuring KIF4A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 49 DNMT3B complex Database 1.05


Categories featuring KIF4A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0005694 chromosome Database 3.87
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0005876 spindle microtubule Database 0.68
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0030496 midbody Database 0.39
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members Pathway Pathway_1136 REACTOME_RECYCLING_PATHWAY_OF_L1 0 0.04
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0006996 organelle organization Database 0
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0


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