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Query: KDM4A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KDM4A 0 -0.923 1.040 -0.260 -0.576

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KDM4A Ubiquitylation K893 -0.347 _AK(gl)GALQSITAGQK_
KDM4A Ubiquitylation K251 -0.699 _MTLISPLMLK(gl)K_
KDM4A Ubiquitylation K252 -0.699 _MTLISPLMLK(gl)K_
KDM4A Ubiquitylation K105 -1.070 _IANSDK(gl)YCTPR_
KDM4A Ubiquitylation K820 -1.283 _SPVDVSK(gl)IPLPR_

Background Information for KDM4A:





Protein-protein Interactions for KDM4A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABHD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KDM4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF414 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KDM4A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Tudor IPR002999 0.28
Category members TF_JmjN IPR003349 0.08
Category members JmjC_dom IPR003347 0


Protein complexes (CORUM database) featuring KDM4A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2183 Kaiso-NCOR complex Database 0


Categories featuring KDM4A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0035064 methylated histone residue binding Database 0.53
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0014898 cardiac muscle hypertrophy in response to stress Database 0
Category members GO Category GO:0016577 histone demethylation Database 0
Category members GO Category GO:0051864 histone demethylase activity (H3-K36 specific) Database 0
Category members GO Category GO:0070544 histone H3-K36 demethylation Database 0


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