bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: KARS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KARS 0 2.519 -1.130 1.650 0.084 -0.672 -0.378 0.796 0.367

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for KARS:


Pubmed-KARS »
Uniprot-KARS »
Biogrid-KARS »
ProteomicsDB-KARS »

Tumorportal-KARS »
COSMIC-KARS »
GenomeRNAi-KARS »
Genecards-KARS


Protein-protein Interactions for KARS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PKN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait KARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KARS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members Asp/Asn-tRNA-synth_IIb IPR002312 0.4
Category members NA-bd_OB_tRNA IPR004365 0.35
Category members aa-tRNA-synth_II IPR006195 0.24
Category members aa-tRNA-synt_II IPR004364 0.15
Category members Lys-tRNA-synth_II_C IPR018149 0


Protein complexes (CORUM database) featuring KARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3040 Multisynthetase complex Database 1.78


Categories featuring KARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_201 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0 3.57
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members GO Category GO:0008033 tRNA processing Database 0.39
Category members GO Category GO:0016597 amino acid binding Database 0.11
Category members GO Category GO:0017101 aminoacyl-tRNA synthetase multienzyme complex Database 0.11
Category members Disease phenotype Autosomal_recessive_nonsyndromic_sensorineural_deafness_type_DFNB Autosomal recessive nonsyndromic sensorineural deafness type DFNB Database 0.04
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0004824 lysine-tRNA ligase activity Database 0
Category members GO Category GO:0006430 lysyl-tRNA aminoacylation Database 0
Category members GO Category GO:0015966 diadenosine tetraphosphate biosynthetic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


.

© Copyright Svejstrup Laboratory 2015