bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: IREB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IREB2 0 -0.499 -0.280 -0.190

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IREB2 Ubiquitylation K860 0.906 _DWAAK(gl)GPYLLGVK_
IREB2 Ubiquitylation K803 0.505 _GTFANIK(gl)LFNK_
IREB2 Ubiquitylation K461 0.236 _VAVTDMK(gl)SDFQACLNEK_
IREB2 Ubiquitylation K404 0.190 _AK(gl)LESMETYLK_
IREB2 Ubiquitylation K611 0.037 _QGDLVTCGILSGNK(gl)NFEGR_
IREB2 Ubiquitylation K769 -1.464 -0.009 _NSAAAK(gl)YLTNR_
IREB2 Ubiquitylation K696 -1.215 -0.023 _IEMGNK(gl)R_
IREB2 Ubiquitylation K847 -0.038 _EGIPLIILAGK(gl)K_
IREB2 Ubiquitylation K848 -0.038 _EGIPLIILAGK(gl)K_
IREB2 Ubiquitylation K107 -0.118 _EAVK(gl)TLGGDPEK_
IREB2 Ubiquitylation K34 -0.190 _LGTK(gl)YDVLPYSIR_
IREB2 Ubiquitylation K475 -0.206 _VGFK(gl)GFQIAAEK_
IREB2 Ubiquitylation K413 -0.308 _AKLESM(ox)ETYLK(gl)AVK_
IREB2 Ubiquitylation K72 -0.991 _TK(gl)QSNVEVPFFPAR_
IREB2 Ubiquitylation K160 -0.994 _LSPLK(gl)VQPK_

Background Information for IREB2:


Pubmed-IREB2 »
Uniprot-IREB2 »
Biogrid-IREB2 »
ProteomicsDB-IREB2 »

Tumorportal-IREB2 »
COSMIC-IREB2 »
GenomeRNAi-IREB2 »
Genecards-IREB2


Protein-protein Interactions for IREB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC20 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait ALDH3B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARL15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENSA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IREB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AconitaseA/IPMdHydase_ssu_swvl IPR000573 0
Category members Acoase/IPM_deHydtase_lsu_aba IPR001030 0
Category members Aconitase/Fe_reg_2 IPR006249 0
Category members Aconitase/3IPM_dehydase_swvl IPR015928 0


Protein complexes (CORUM database) featuring IREB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IREB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0006782 protoporphyrinogen IX biosynthetic process Database 0
Category members GO Category GO:0006826 iron ion transport Database 0
Category members GO Category GO:0006879 cellular iron ion homeostasis Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0010040 response to iron(II) ion Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0030316 osteoclast differentiation Database 0
Category members GO Category GO:0030350 iron-responsive element binding Database 0
Category members GO Category GO:0032526 response to retinoic acid Database 0
Category members GO Category GO:0034101 erythrocyte homeostasis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050892 intestinal absorption Database 0
Category members GO Category GO:0051539 4 iron, 4 sulfur cluster binding Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


.

© Copyright Svejstrup Laboratory 2015