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Query: IGF2BP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IGF2BP3 0 0.440 0.270 -0.640 -0.052 -0.850 -0.420 0.103 0.530

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IGF2BP3 Phosphorylation T528 0.210 0.270 _DQT(ph)PDENDQVVVK_
IGF2BP3 Ubiquitylation K272 -0.328 -0.293 _EAQDIK(gl)FTEEIPLK_
IGF2BP3 Ubiquitylation K450 -1.812 -0.838 _IAPAEAPDAK(gl)VR_
IGF2BP3 Ubiquitylation K567 -1.268 -1.607 _QHQQQK(gl)ALQSGPPQSR_
IGF2BP3 Ubiquitylation K190 -1.912 _QGSPGSVSK(gl)QKPCDLPLR_

Background Information for IGF2BP3:


Pubmed-IGF2BP3 »
Uniprot-IGF2BP3 »
Biogrid-IGF2BP3 »
ProteomicsDB-IGF2BP3 »

Tumorportal-IGF2BP3 »
COSMIC-IGF2BP3 »
GenomeRNAi-IGF2BP3 »
Genecards-IGF2BP3


Protein-protein Interactions for IGF2BP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IGF2BP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IGF2BP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring IGF2BP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring IGF2BP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0003730 mRNA 3'-UTR binding Database 0.24
Category members GO Category GO:0045182 translation regulator activity Database 0.18
Category members GO Category GO:0048027 mRNA 5'-UTR binding Database 0.08
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0042035 regulation of cytokine biosynthetic process Database 0


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